Dr Dingle's Blog / phthalates

Phthalates in plastics linked with eczema (and dozens of other health conditions)

Phthalates in plastics linked with eczema (and dozens of other health conditions)

Phthalates are synthetic chemicals used in food wrappings, cosmetic products and personal care products, children’s toys, cleaning products,and other consumer products because of their properties of transparency, durability, and flexibility. One of the major exposures to phthalates is through the use of personal care products and ingestion (including dietary ingestion and incidental ingestion. The ubiquitous presence of phthalates in the environment and the potential consequences of human exposure to phthalates have raised concerns, particularly in vulnerable populations such as pregnant women and infants as exposure to toxic pollutants during these period can result in an increased risk of adverse health outcomes later in life.

Animal as well as epidemiological studies in infants and children have found various health effects of specific phthalates, including abnormal reproductive outcomes, children’s neurodevelopmental and behavioral problems, and asthma and allergies. They are also linked with breast and prostate cancer and hormonal and thyroid imbalances in adults.

During development in the womb, the skin of the fetus may be exposed to various products absorbed by the mothers, including phthalates given that some phthalates have been detected in amniotic fluid. Later in life, children’s dermal exposure can occur through the use of emollients, personal care products, and dermal contact with plastic products.

In a study of 604 mother son pairs and building on the research of many before them, found a strong link between mothers exposure and eczema at 5 years of age.

The best way to reduce your exposure to phthalates is reduce your exposure in personal care products. don't microwave in plastic containers and don't store food in plastic.

Dangerous Beauty. The truth about personal care products and make up. https://www.drdingle.com/collections/frontpage/products/dangerous-beauty-1

source of study

https://ehp.niehs.nih.gov/ehp1829/

 

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Men also exposed to chemicals from Personal care products (PCPs). New study

Men also exposed to chemicals from Personal care products (PCPs). New study

In this study of four hundred men 83% percent increase in monoethyl phthalate (MEP) was associated with use of cologne/perfume and 74% for deodorant. While the largest percent increase for parabens, between 66 and 156% was associated with the use of suntan/sunblock lotion and a 79–147% for hand/body lotions. Increases in MEP and parabens were generally greater with PCP use within 6 h of urine collection. A 6 hour period after application of the PCP lead to at least 70% of the weighted score and predicted a 254–1,333% increase in MEP and parabens concentrations.

Previous studies have shown a cyclical pattern of rise and decline suggestive of ongoing repeated nonfood exposures including monoethyl phthalate increasing after showers, which suggested PCPs as a major source of DEP exposure.

Phthalates are a family of chemicals commonly used as plasticizers in polyvinyl chloride plastics and in consumer products, including personal care products (PCPs), medications, and food processing and packaging materials. However, studies suggest the major phthalate and paraben exposure comes from personal care producs and cosmetics, up to 50 times more for parabens in women than diet. Diethyl phthalate (DEP) is the most commonly used phthalate in PCPs. Parabens are a family of chemicals with antimicrobial preservative properties that are also widely used in PCPs, pharmaceuticals, food, and beverages to increase the shelf life of the product. Methylparaben, propylparaben, and butylparaben are most commonly used in PCPs.

A number of studies have also shown now that that urinary concentrations of the parabens are lower when the participants are given products without parabens and phthalates.

Exposure to phthalates and parabens from PCP use occurs through direct dermal application or even transdermal exposure from air.

The phthalates and parabens are endocrine disruptors and have been linked to adverse health outcomes including male infertility.

Source: https://doi.org/10.1289/EHP1374

https://www.drdingle.com/products/dangerous-beauty-1

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Europe says BPA (bisphenol A) is an endocrine disruptor and needs to be regulated more heavily

Europe says BPA (bisphenol A) is an endocrine disruptor and needs to be regulated more heavily

BPA has received a lot of media attention over the last decade, primarily the effects of this chemical on our reproductive health and infants.

This week the European Chemicals Agency (ECHA) has classified bisphenol A, a chemical found in many common plastic products, as an endocrine disruptor and a ‘substance of very high concern’ due to its “probable serious effects to human health which give rise to an equivalent level of concern to carcinogenic, mutagenic, toxic to reproduction substances”.

France banned BPA in baby bottles in 2010 and in food containers in 2012. The new European classification for BPA follows a proposal by the French food security agency (ANSES) from February this year. ECHA’s member state committee, made up of representatives from all 28 EU countries, agreed the change unanimously on 16 June.

But nothing in Australia?

Despite its widely known health effects BPA is still used in a variety of consumer products containing epoxy resins, polyester-styrene, and polycarbonate plastics. It is added to various plastics in many different consumer products including plastic bottles while epoxy resins are used as protective coatings for metal food and beverage cans. It is found in every can and most plastic bottles unless they are labelled BPA free. Bisphenol A is extensively used in the food-packaging industry so even food take away wrappers may be contaminated with BPA. It is also found in thermal paper for receipts and fax, however, human exposure occurs mainly from the direct contact of food with Bisphenol A containing plastics. Other exposure routes that are of particular concern are Bisphenol A leaching from babies’ feeding bottles, and Bisphenol A BPA leaching from dental fillings and sealants. In one study BPA was detected in 15 conventional samples, including dish and laundry detergent, tub and tile cleaner, soaps, lotions, shampoo, conditioner, shaving cream, nail polish, and sunscreen. Overall, human exposure to BPA is frequent and widespread, and more than 90% of individuals have detectable amounts of BPA in urine as reported by studies around the world. In a study in the USA BPA was found in 92.6% of urine samples from 2,517 people across the country.

BPA was first reported to impact the reproductive system of female rats in the 1930s. Since then there have been hundreds of published studies showing BPA effects in animals even at very low levels (μg/kg/d) and at levels we would normally be exposed to on a daily basis. It appears that these low levels may even be more of problem on health that much higher levels.

I have written extensively on this in my new book Dangerous Beauty

https://www.drdingle.com/products/dangerous-beauty-pre-release

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Europe says BPA (bisphenol A) is an endocrine disruptor and needs to be regulated more heavily

Europe says BPA (bisphenol A) is an endocrine disruptor and needs to be regulated more heavily

BPA has received a lot of media attention over the last decade, primarily the effects of this chemical on our reproductive health and infants.

This week the European Chemicals Agency (ECHA) has classified bisphenol A, a chemical found in many common plastic products, as an endocrine disruptor and a ‘substance of very high concern’ due to its “probable serious effects to human health which give rise to an equivalent level of concern to carcinogenic, mutagenic, toxic to reproduction substances”.

France banned BPA in baby bottles in 2010 and in food containers in 2012. The new European classification for BPA follows a proposal by the French food security agency (ANSES) from February this year. ECHA’s member state committee, made up of representatives from all 28 EU countries, agreed the change unanimously on 16 June.

But nothing in Australia?

Despite its widely known health effects BPA is still used in a variety of consumer products containing epoxy resins, polyester-styrene, and polycarbonate plastics. It is added to various plastics in many different consumer products including plastic bottles while epoxy resins are used as protective coatings for metal food and beverage cans. It is found in every can and most plastic bottles unless they are labelled BPA free. Bisphenol A is extensively used in the food-packaging industry so even food take away wrappers may be contaminated with BPA. It is also found in thermal paper for receipts and fax, however, human exposure occurs mainly from the direct contact of food with Bisphenol A containing plastics. Other exposure routes that are of particular concern are Bisphenol A leaching from babies’ feeding bottles, and Bisphenol A BPA leaching from dental fillings and sealants. In one study BPA was detected in 15 conventional samples, including dish and laundry detergent, tub and tile cleaner, soaps, lotions, shampoo, conditioner, shaving cream, nail polish, and sunscreen. Overall, human exposure to BPA is frequent and widespread, and more than 90% of individuals have detectable amounts of BPA in urine as reported by studies around the world. In a study in the USA BPA was found in 92.6% of urine samples from 2,517 people across the country.

BPA was first reported to impact the reproductive system of female rats in the 1930s. Since then there have been hundreds of published studies showing BPA effects in animals even at very low levels (μg/kg/d) and at levels we would normally be exposed to on a daily basis. It appears that these low levels may even be more of problem on health that much higher levels.

I have written extensively on this in my new book Dangerous Beauty

https://www.drdingle.com/products/dangerous-beauty-pre-release

Read more →

Toxic Teflon

Toxic Teflon

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are persistent synthetic chemicals that are widely used in industrial applications and often detectable in humans. Some PFASs have a long half-life (how long it takes for half of the chemical to break down and be eliminated from the body) in humans. For example, the half-life of perfluorooctanoate (PFOA- which is used in the production of teflon), perfluorooctane sulfonate (PFOS), and perfluorohexanesulfonate (PFHxS) has been estimated at 3.8, 5.4, and 8.5 years, respectively. That is, they will be in your body for a many years even after one exposure.

In rats, PFASs can interfere with the estrous cycle and have been linked with reduced fecundity, indicated by increased time to pregnancy (TTP) and risks of infertility. Dysfunction of menstrual cycle is a major cause of infertility and lower fecundity. Animal and human evidences suggest that PFASs affect formation of steroid hormones and hormone levels manifesting in altered menstrual cycles such as prolonged lengths. A recent epidemiologic study suggested that menstrual cycles may be lengthened in women with the highest serum concentrations of PFOA in comparison to those with the lowest concentrations.

In this study of PFASs in 950 pre-pregnant women with higher levels had increased odds of self-reported history of irregular menstrual cycle, long menstrual cycle and levels were negatively associated with self-reported history of menorrhagia. The study concluded that certain PFASs are associated with abnormal menstruation in humans. https://doi.org/10.1289/EHP1203

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Phthalates one step closer to being banned in Europe.

Phthalates one step closer to being banned in Europe.

In 2015 The EU banned the use of 4 phthalates (butylbenzyl phthalate (BBP), di(2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP), and diisobutyl phthalate (DIBP)) but companies could seek—and have obtained—continued-use authorizations if there are no safer alternatives. However, very recently on June 20 2017, the EU went further and voted to remove the chemicals from consumer products that contain the phthalates at levels greater than 0.1% by weight by getting rid of any exemptions.

Phthalates are industrial chemicals often used to soften plastics in toys, household items such as food containers, and medical devices as well as construction materials, floorings, paints, lubricating oils, wood finishes, detergents, industrial plastics, pharmaceuticals, and as a plasticizer for polyvinyl chloride products. Phthalates have been increasingly added to cosmetic products such as perfumes, lotions, hairsprays, moisturisers, nail polish, deodorants, and ingredients in makeup, shampoos and soaps. They are used primarily at concentrations of less than 10% as plasticizers in products such as nail polishes (to reduce cracking by making polished nails less brittle) and hairsprays (to help avoid stiffness by allowing them to form a flexible film on the hair) and as solvents and perfume fixatives in various other products. Phthalates produce oily textures in lotions and they contribute to making skin feel soft and helping lotions penetrate deeper into the skin.

Some phthalates are included in personal care products because of their ability to hold colour, denature alcohol, and fix fragrance. Phthalates are also used as a fragrance base and as components of fragrances to make scents last longer. If a product’s label lists “fragrance” or “parfum,” it’s possible, even probable, that it contains phthalates (and parabens), as companies are not required to disclose fragrance components. Fragrance has emerged as the strongest predictor among PCPs of urinary concentrations of certain phthalate metabolites. In a 2012 study, the highest concentration of one particular phthalate was found in fragrance/perfume and car air freshener. Other products with high concentrations include car interior cleaner, tub/tile cleaner, bar soap, shaving cream, and lipstick. Interestingly, three different phthalates were found in so-called “alternative” products. These compounds may have been introduced as substitutes for the better-known anti-androgenic (testosterone) phthalates, even though they are also endocrine-disrupting chemicals.[2] An “alternative” shaving cream contained five different phthalates, illustrating the potential for simultaneous exposures to multiple phthalates, which act cumulatively and may act synergistically. What is worrying is that none of the products that were tested had “phthalate” on the label—including personal care products, which by law are required to list phthalates unless they are part of a secret fragrance ingredient. However, the conventional nail polish sample with measurable phthalate contained a product labelled “phthalic anhydride copolymer” which is just another phthalate. Phthalates are seldom listed on product labels in most countries because current regulations do not require listing individual fragrance components. It is obvious now that products marketed as “natural” may also contain phthalates, even though the consumer believes them to be “chemical-free.”

 

http://cen.acs.org/articles/95/i26/European-Union-further-restricts-four.html

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Sickness from the smelling industry and the health effects of fragrance compounds.

Sickness from the smelling industry and the health effects of fragrance compounds.

In the past few decades, synthetic fragrance compounds have become ubiquitous components of personal care and household cleaning products. Overwhelming consumerism trends have led to the excess usage of these chemicals. It has been observed that this fragrance-laden unhealthy lifestyle runs parallel with the unprecedented rates of diabetes, cancer, neural ailments, teratogenicity, and transgender instances. The link between fragrances as and the health outcomes can remain latent for decades.

The adverse effects of the fragrance constituents as phthalates, paraben, glutaraldehyde, hydroperoxides, oil of turpentine, metals, nitro musks, and essential oils, among others, are being identified. The endocrine-immune-neural axis pathways of these chemicals are being proven. Despite this a majority of the vulnerable populations are unaware and unmotivated to avoid these 'slow poisons'. Possible mechanism for thier action include acidosis, aromatase upregulation, estrogen hyperproduction and inflammation.

Fragrance compounds share structural similarity with carcinogenic environmental hydrocarbons are able to mimic estrogen, the powerful signaling hormone, which underlies the majority of morbidities.

 

source

https://www.ncbi.nlm.nih.gov/pubmed/28478814

 

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Chemicals found in makeup and frying pans have again been linked with early menopause.

Chemicals found in makeup and frying pans have again been linked with early menopause.

Studies have found around 15 chemicals that are positively associated with younger menopausal age and the two major culprits were phthalates found in everyday makeup and personal care products.
Of the 13 chemicals the strongest influence was 3.8 years younger for mono-(2-ethyl-5-hydroxyhexyl)phthalate, compared with less-exposed women.
Another study found a link between early menopause and elevated serum levels of perfluorooctanoic acid (PFOA), or teflon an industrial chemical used in several nonstick and stain-repellant applications. Manufactured for decades, PFOA is now widespread in the biosphere, and most people have some in their bodies. The chemical accumulates in blood, so women of reproductive age will eliminate some of it when they menstruate.
This result was also found in two prior studies of polyfluoroalkyl chemicals (PFCs) including PFOA.

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2017 Dr Dingle’s February Wellness Presentations.

2017 Dr Dingle’s February Wellness Presentations.

7.00 -9.00 PM. Wednesday nights

445 Charles St North Perth

$12 online/$20 at the door www.drdingle.com

February 1, 2017 : Probiotics, People and Poo 

http://tix.yt/probiotics   February 8, 2017 : Reducing Toxic Overload in our Kids 

http://tix.yt/toxic-kids February 15, 2017 : 7 Steps To Permanent Weight Loss 

http://tix.yt/7stepstoweightloss

February 22, 2017 : Living Longer, Ageing Well. The science of living a full life http://tix.yt/ageingwell

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Reducing toxic chemical exposure reduces the risk of diabetes

Reducing toxic chemical exposure reduces the risk of diabetes

New research suggests that a 25% reduction in exposure to just 4 chemicals commonly found in the home would reduce diabetes cases by around 13% which could save billions of dollars in annual health costs.
 
Increasing evidence suggests that synthetic chemicals commonly found in the environment contribute to metabolic disorders, especially obesity and diabetes. Previous publications have associated prevalent diabetes with polychlorinated biphenyls (PCBs), persistent chlorinated pesticides, phthalates and perfluoroalkyl substances (PFASs). Separate studies found similar connections between diabetes and exposure to DDT, PCBs and perfluoroalkyl.

In this study of 1,016 participants they found significant connections between the four chemicals investigated and a number of different diseases and found reduced exposure to all four chemicals would lead to a likely reduction 13% in diabetes cases. This study confirms substantial contribution, especially of mixtures of endocrine-disrupting chemicals, to adult type 2 diabetes, and large annual costs of medical care. A previous reported a significant positive relationship between phthalates in the blood and lowered insulin secretion, increased insulin resistance or both.
    
While this study supports efforts to reduce chemical exposures to reduce the burden and costs of diabetes there are many other disease states including cardiovascular disease and cancer that would also likely be reduced.

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