Dr Dingle's Blog / food

Vegetable oils and margarine are no better than saturated animal fats for the heart.

Vegetable oils and margarine are no better than saturated animal fats for the heart.

More evidence from the best controlled randomised controlled trials found that replacing saturated fats with mostly vegetable-seed oils (n-6 PUFA) does not reduce coronary heart disease mortality or total mortality.

So why does the heart foundation continue to sell margarine and vegetable oils to the public?

A cornerstone of outdated dietary advice is the recommendation to reduce the intake of saturated fatty acids (SFA) as a means of reducing the risk of coronary heart disease (CHD). There are a few variations of this recommendation, these include: 1) advice to reduce the intake of SFA; 2) advice to replace SFA with monounsaturated fatty acids (MUFA) and mostly n-6 polyunsaturated fatty acids (PUFA); and 3) advice to replace SFA with mostly n-6 PUFA. It also recommends margarine and vegetable oils instead of butter and animal fats. However, the evidence for this recommendation has been questioned by recent a number of meta-analyses of observational studies and clinical trials. These studies have consistently found that the intake of SFA is not independently associated with the incidence of CHD.

Unfortunately, mega 6 oils such as corn, safflower, cottonseed, sunflower, and soya are now in nearly all our foods. Apart from the obvious consumption of vegetable oils and margarine you buy in the supermarket—which I hope you are now not going to buy—Omega 6 oils are hidden in most foods. You will find vegetable oils in just about every processed and semi-processed food including bread, cakes, and breakfast cereals and in lots of the plant-based drinks like almond or soya milk the main ingredient is often vegetable oil. All the takeaway foods, frozen and packaged dinners have Omega 6 oils. Even the “new” Mediterranean diet is laden with Omega 6 oils. When you buy olives, pesto sauce, sundried tomatoes or anything soaking in oil it is now vegetable oil in which it is soaked, not olive oil because vegetable oil is cheaper, unless you go to Italy where most foods are still soaked in olive oil. It is almost impossible to get away from the excess of Omega 6 oils. Time to read the labels! Factory produced eggs have 20 times more Omega 6 than Omega 3 compared to free-range eggs, which have a ratio of 1:1. Similarly, grain-fed beef (which I do not recommend you eat) has around 20:1 Omega 6 to Omega 3 oils because the cows are fed grains rich in Omega 6 oils. Alpha linolenic acid is found in the grass and is converted into the important Omega 3 oils by the animals. It is found only in grass-fed animals. Grass-fed cows are also a lot less stressed and have as a result lower levels of inflammation.
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Health Effects of Poor Sleep

Health Effects of Poor Sleep

Sleep is as important to the human body as food and water, but most of us still don’t get enough sleep. We obtain treatment for illness or injury – yet we generally fail to seek help when we aren’t getting enough sleep. The average length of sleep has declined from around 9 hours a hundred years ago to seven hours today. And the depth of sleep has also declined.

Sleep is complicated in the way that there are many different factors that influence the effectiveness of sleep. It’s not just duration that determines the effectiveness of sleep, factors such as quality, frame of mind and deepness all contribute to the maximum desired outcome and even our perception of how we sleep. Many factors can play a part in the quality and quantity of our sleep.     

On average a healthy person will spend around one third of their life sleeping.  Inadequate hours of good quality sleep leads to a disruption to vital biological processes resulting in a decrease in mental and physical health including impaired cognitive function and lower productivity and work performance due to a decrease in attention, judgment and responsible decision making. 

Numerous studies have also shown that even a little bit of sleep deprivation decreases efficiency and increases risk of disease, including cardiovascular disease, diabetes and cancer.  Some of the physical effects found from long term fatigue are heart disease, diabetes, high blood pressure, gastrointestinal disorders, depression eating disorders and weight gain. Sleep deprivation has also been shown to negatively affect endocrine (hormones) and metabolic functioning as well as nervous system balance. A recent meta-analysis which included 122,501 subjects found that insomnia determined an increased relative risk of 45% of developing or dying from cardiovascular disease during the follow-up.

Sleep debt has been found to lead to elevated evening cortisol levels and impaired glucose tolerance and is a risk factors for the development of insulin resistance and perhaps type 2 diabetes.

Obesity is another disorder linked with sleep with sleep deprivation. Many studies, including one spanning twenty years, have shown increasing weight gain with poor sleep. Shift workers for example are known to be a high-risk group for obesity.

While many factors can contribute to insomnia and poor sleep undoubtedly the most important one in the twenty first century is stress. Increasing research shows that there is an activation of the stress-response system and the degree of sleep disturbance experienced correlates with the level of stress-response activation and that insomniacs and others with poor sleep patterns experience more psychological stress.

Unfortunately, there can be a vicious cycle of stress poor sleep and more stress. If you are not getting enough sleep, you have to rely more and more on your alarm clock, and if you oversleep and wake up already fatigued. Thus, a person who is always feeling tired – even after a good night’s sleep – may have overworked adrenal glands.

Cortisol levels are highest in the morning and decrease gradually throughout the day.  The body develops a routine, and cortisol is secreted at roughly the same amounts at a particularly time of day, depending on levels of stress.  If an individual does not receive enough sleep they will produce more cortisol than they would on a normal routine day. Studies also show that stress and elevated levels of cortisol actually inhibit the ability to fall asleep, further exacerbating stress symptoms.

In another study although all subjects reported equivalent numbers of daily stressful events, people with insomnia found the impacts of these events to be more severe. Insomniacs also experienced major life events more intensely, were much more alert before bedtime, viewed their lives as more stressful, and used emotionally-based coping strategies to deal with stress more often than did the normal sleeper group. It appears that although normal sleepers and insomniacs experience similar types of stressful inputs in insomniacs the stress-response is more sensitive to these inputs and its activation leads to lack of sleep.

The effects of sleep deprivation can include fatigue, reduced productivity, slower reflexes and reactions, moodiness and a lack of energy, mimicking many of the characteristics of stress. The more hours we spend awake, the more sluggish our minds become, according to the findings. One night without sleep reduces our brains ability to take in new information by nearly 40 percent, due to a shutdown of brain regions during sleep deprivation. Impaired sleep function decreases the neuroplasticity in the central nervous system resulting in diminished cognitive function as impulse transmission are impaired. Sleep is the regenerative time for the Central nervous system and nerves, without which brain atrophy and weakened conduction can result.

Brains that are sleep deprived aren’t as efficient and have to work harder. Exactly want you don’t want. Studies show the brains of the sleep deprived desperately pumping energy into the prefrontal cortex, trying to overcome the effects of sleep deprivation.

Sleep plays an important role in consolidating memories. While we sleep, our brain orders, integrates and makes sense of things that have happened to us. Not only that, but we seem to consolidate our learning while we sleep. Without sleep the process is badly disrupted, meaning it’s difficult to lay down long-term memories and it’s harder to learn new skills. Sleep deprivation causes many of the powers of focus and attention to decline which partly explains the distracted feeling you get when tired. Sleep deprived people easily get stuck in thinking loops and as a result fall back on the brain’s automated systems, our habits.

Perhaps it is time we valued sleep more and turned off the TV and computer earlier so we can be healthier and smarter the next day. 3 extra steps you can try to reduce stress related poor sleep include;

Meditate a few minutes before you go to sleep;

Try a sleep supplement from your local health food store; and

Don’t eat late and go for a little walk after dinner.

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Are your medications making you (Pharmaceutical) fat?

Are your medications making you (Pharmaceutical) fat?

Most people don't realise that a large number of pharmaceutical agents, including many over-the-counter and prescription drugs, are linked with weight gain and obesity. Drug-induced weight gain is a serious side effect of many commonly used drugs. The weight gain can be extremely high in a relative short time: sometimes more than 10 kg over 12 months. Some medications can increase appetite, cause fluid retention, or slowly lead to weight gain over a period of time due to fatigue and lower activity.
The best know impact, however, is the role of antibiotics in weight gain. The growth (fat) promoting effects of antibiotics were first discovered in the 1940s. Since then, antibiotics administered in low doses have been widely used as growth promoters in the agricultural industry worldwide. As a result, the largest use of antibiotics and related antimicrobial substances is on farms, with low doses fed to large numbers of animals used for food production, to increase weight gain by as much as 15%. If antibiotics are so effective in causing weight gain in farm animals, similar results are likely to occur in human populations. Unfortunately, antibiotic use in humans has increased markedly, often for the wrong reasons, now approximating one antibiotic course per year for the average child and most of them for the wrong reason. Antibiotics can cause many problems and we do overuse them. For a bacterial, not viral, infection always listen to you health professional; the gut microbiome can be rebuilt after the treatment finishes with super probiotics and prebiotics.
 
Blood pressure lowering medications such as Beta blockers reduce metabolic rate and slow utilization of nutrients, thus resulting in weight gain. Obesity and hypertension contribute to metabolic syndrome, which could further complicate the patient’s situation. Many of the diabetes medications can lead to weight gain. These agents may increase insulin production, which can lower blood sugar levels and result in an elevated appetite. Injectable insulin itself can also lead to weight gain, possibly due to periods of low blood sugar that stimulate appetite. Other drugs used in the treatment of type 2 diabetes can lead to weight gain and fluid retention.
Many psychotropic drugs, including antipsychotics, antidepressants and mood stabilizers, are also linked with significant weight gain. In a study of three antipsychotic drugs over 12 months, at three months haloperidol added 3.8 kg, risperidone 5.9 kg and 8.4 kg for olanzapine. After one year, all participants had gained between 9 and 11 kg. Some antidepressant drugs induce significant body weight gain, which may amount to 20 kg over several months of treatment. The older antidepressants, known as tricyclic antidepressants (TCAs) are notorious for increasing appetite and causing weight gain.
Commonly prescribed oral glucocorticoids like prednisone can also cause significant weight gain, especially when taken over prolonged durations, by causing fluid retention, stimulating appetite and increasing deposits of fat in the upper part of the body and the abdomen. Antihistamine drugs that are used to treat allergies can result in weight gain through blocking of a chemical called histamine in the brain. Weight gain is a common side effect of drugs used for headache prevention.
Statin drugs used to lower cholesterol have now been shown to be ineffective in prevention of heart disease. However, they are associated with an increase in diabetes and weight gain.
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Sleep is Important

Sleep is Important

 

Sleep has been shown to be as important to the human body as food and water, but most of us still don’t get enough sleep. We obtain treatment for illness or injury – yet we generally fail to seek help when we aren’t getting enough sleep. The average length of sleep has declined from around 9 hours a hundred years ago to seven hours or less today. And the depth of sleep has also declined.

Sleep is complicated in the way that there are many different factors that influence the effectiveness of sleep. It’s not just duration that determines the effectiveness of said sleep, factors such as quality, frame of mind and deepness all contribute to the maximum desired outcome and even our perception of how we sleep. Many factors can play a part in the quality and quantity of our sleep and to maximize our sleep time an understanding of this is essential.     

On average a healthy person will spend around one third of their life sleeping.  Sleep is considered a natural periodic state of rest for the mind and body, in which the eyes will usually close and consciousness is completely or partially lost resulting in a decrease in bodily movements and responsiveness to external stimuli. Inadequate hours of good quality sleep leads to a disruption to vital biological processes resulting in a decrease in cognitive function mental and physical health including impaired work performance due to a decrease in attention, judgment and responsible decision making. 

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The Drawbacks of Cooking

The Drawbacks of Cooking

Cooking and processing food is something that is widely accepted, but many of us don't realise that there may be nutritional drawbacks. High heat, as well as many of the cooking processes, alters the physical and chemical structure of food, changing how it is digested and the nutrients that are available to be absorbed. Enzymes are destroyed and nutrients can be lost from almost all forms of cooking, depending upon the type of cooking, temperature, pH, oxygen content and type of food. In addition, the processing of foods may add toxins, which can build up in the body, causing a negative effect on health.

Vegetables, provide a good example of how cooking reduces the amount of valuable nutrients. With vegetables, cooking by means of boiling or steaming produces three composition-changing actions: shrinkage due to the extrusion of vegetable juices; leaching by either boiling water or condensed steam; and hydration.

Leaching produces a higher loss of water-soluble nutrients in vegetables, which increases with duration of boiling and the quantity of water used. Between 70 and 80% of vitamins and minerals including vitamin C and B group (such as thiamine and folate), and potassium are lost during the boiling process. Steaming vegetables does not result in the loss of anywhere near as many nutrients into the water as with boiling; however steamed vegetables still may lose up to 30% of their water and water-soluble nutrients. As the nutrients leach into the cooking liquid, that full value of the vegetable can only be maintained, if this is consumed as well as the solid food.

In experiments, the boiling of spinach and broccoli removed between 51% and 56% of folate. Thiamine (B1) has one of the highest losses by cooking—up to 80% with complete loss from oven-roasted food, while boiled legumes had 50% thiamine loss. Riboflavin (B2) losses tend to be less but still significant; roast chicken retained only 22% of its riboflavin after cooking.

The fat-soluble vitamins, A, D, E and K, are not lost whilst boiling, because they are not water-soluble, though they are still prone to oxidation damage, through high heat. However, other cooking processes can certainly have a big impact on the levels of the fat-soluble vitamins. Oven roasting lamb chops decreased the vitamin A content by 58%. Similarly, baking fish reduced vitamin A content by 37%. Many foods lose between 19 and 57% of the carotenoids, beta-carotene and xanthophylls when cooked.

The minerals that form the most soluble salts, potassium and sodium, have the highest loss using wet (boiling and streaming) cooking methods. In an experiment, boiled fish lost 25% of its potassium and 60% of its sodium. Pressure-cooking resulted in losses of 51% of sodium and 71% of potassium in mangrove seeds. Boiling of some vegetables (mushrooms and asparagus) reduces their selenium content by between 29% and 44%.

Protein loss through cooking, is minimal, appearing to be around 13%. However, after cooking, proteins become harder to digest as they form cross-links with reducing sugars, meaning the body has to work harder to break down, which may lead to the fermentation of raw meat in the digestive system. Raw meat, such as steak tartare and sushi, are much easier to digest, although they are an acquired taste. 

Cooking increases acidosis

Cooking food, alters its natural state, and therefore the way it interacts with the body. Ideally the body should have a neutral pH level, around 7.2 to 7.4, but heavily processed foods and cooked animal proteins can increase the acidity of the body. As a result acidosis (increased acid in the body) decreases the body’s ability to absorb minerals and other nutrients, energy production in the cells and the body’s ability to repair damaged cells.

Heat produced toxic compounds

The higher the cooking temperature, the more food is altered, sometimes into toxic compounds. One study found close to 3,800 heat-formed chemicals in cooked food, including a number of carcinogens. Toxins developed from cooked and processed foods include acrylamide, heterocyclic amines, nitrosamines and polycyclic aromatic hydrocarbons (PAH’s). These substances are all carcinogens. Carcinogens such as acrylamide, which is found in cooked and processed foods, are not found in raw foods. PAH’s, the burnt bits of food (for example, from barbequeing meat or toast), are known to be carcinogenic and are the oldest known chemical carcinogens. In food, more than 10 out of 20 PAH identified have been shown to be carcinogenic in experimental animals. Oral administration at various concentrations in rodents have resulted in stomach, ovarian, lymphoid, mammary and hepatic tumours. The major sources for PAH in food is during heat processing (grilling, smoking, toasting). The formation of PAH is minimal below 400oC, however the amounts increase linearly in the range 400-1000oC or when foods are in direct contact with flames. Smoking also forms a variety of other toxic compounds including nitrogen oxides which can form nitrites and are able to react with amines and amides, yielding N-nitroso compounds (Nitrosamines and Nitrosamides). Formation of these compounds occurs optimally around pH 3.5 and is catalysed by high temperatures. A significant portion of nitrosamines produced during the frying of food is also found in condensed vapours and may be breathed in by people doing the cooking. These nitroso compounds are well known cancer causing chemicals in both human and animal studies.

Various mutagenicity (pre cancer cells) tests also showed positive results related to amino acid pyrolysis (protein cooking) products and are considered potent liver carcinogens in rats and mice. Frying at 143oC for 20 minutes only produced low activity, whereas 191oC and 210oC for up to 10 minutes gave much higher mutagen activities. In meat it appears that only low levels of TA98 mutagenic activity are produced when ground beef is microwaved, stewed, simmered, boiled or deep fat fried. Baking, roasting and broiling produce moderate activity, while frying produces the highest activity.

Increases in time and temperature of cooking have been shown to increase advanced glycation end products (AGEs), which are shown to increase inflammation, particularly in diabetics. AGE products do considerable damage in the circulatory system and are increasingly associated with a range of adverse health effects from which diabetics suffer, including those leading to gangrene and blindness.

Plastics in heating, cooking and Microwaves

Unfortunately a lot of people do not realise that plastics leach out toxic substances in the food and the rates of this release is often dependent on heating and the type of food. So putting hot food into plastic containers or heating food in plastic containers, which is common with microwave cooking, increases the release of different toxic plastic compounds such as PVC, BPA (Bisphenol A) and plasticizers like and phthalates (DEHA).

DEHA is a phthalate like chemical added to plastics to make them more pliable is a known endocrine (hormone) disruptor and causes testicular and reproductive defects in rats. In studies conducted on rats, DEHA has been known to cause androgenic effects. It was also found to have caused developmental toxicity in rat foetuses.

BPA has been found to cause oestrogenic effects in rats in low exposure, a change in maternal instinct in rats at one fifth the level considered safe and that it causes aneuploidy (extra or missing chromosones) in mice. Aneuploidy is the cause of spontaneous miscarriage in humans, and causes between 10 and 20 percent of birth defects, including Down's syndrome. This implicates BPA in a suite of health problems.

“Microwave safe” is not a health claim and has no bearing on the movement of chemicals into the food. Instead it is a warning that the plastic will not physically deteriorate if exposed to microwaves. That is it will not melt. Many of the microwave safe products use polyethylene instead of other plastics such as PVC as polyethylene has no plasticizers. PVC is a known liver cancer causing agent.

A common piece of cookware in most kitchens, teflon cookware is a high temperature cookware that is made with material that enable’s it to heat consistently at a lower temperature to prevent burning, and is more resistant to damage caused by sudden temperature changes, and maintains a non-stick surface. Teflon cookware is formulated from Polytetrafluoroethylene (PTFE) and Perfluorooctanoic acid (POFA), both being toxic substance which are released into the food and into the air.

Cooking with Teflon enables these gases to be released and penetrate the alveoli creating respiratory problems, causes direct damage to cell membranes of the lungs, elevates cholinesterase activity and increases levels of inorganic fluorides in the human body. Although research on the effects of PTFE on human health is limited, extensive animal studies have shown inhalation exposure to produce adverse health effects in several organs and at higher concentrations even death. Rats exposed to high concentrations developed hemorrhages, edema, fibrin deposition in lungs and damage to the proximal tubule of the kidney. Most alarming however, PTFE releases toxic pyrolysis products in the air that can cause rapid death of birds. Exposure of budgerigars to PTFE pyrolysis products in the air for only 9 minutes produced severe clinical signs, lesions and death of 31 of 32 birds. A similar effect on five cockatiels was also observed in an incident where all five had died within 30 minutes of exposure to an over-heated frying pan containing PTFE.

Of additional concern to the manufacturing of Teflon cookware is the inclusion of Perfluorooctanoic acid (PFOA) in its’ non-stick coating. Perfluorooctanoic acid is linked to damaging the human immune system, altering the endocrine system, causing infertility, damaging children’s health and producing development problems, and to be carcinogenic. One study found PFOA production workers in the U.S. have a three-fold increase in developing prostate cancer. The U.S. EPA state that not only is PFOA a likely cancer carcinogenic, exposure to the chemical also impairs the fertility of women. While exposure to PFOA in utero (to the fetus) has been linked with reductions in newborn birth weight and adverse effects on the skeletal and organ development of the baby. Exposure to POFA from Teflon cookware alters the endocrine system including decreased levels of reproductive hormones and disrupted thyroid hormone regulation.

Other than the emissions from Teflon cookware into the air lesser known side effect of cooking is the creation of indoor combustion air pollutants. Carbon monoxide (CO), nitrogen dioxide (NO2), and particulate matter (PM) are harmful air pollutants that pose significant short- and long-term health risks. These same pollutants are also some of the most common contributors to unhealthy air inside homes, due in part to cooking. Researchers now understand that the process of cooking food and even simply operating stoves—particularly gas appliances—can emit a cocktail of potentially hazardous chemicals and compounds. Within our homes, these pollutants are less diluted than they are outdoors, and in the absence of proper ventilation, they often are trapped inside. Literally millions of people are routinely being exposed to air pollutants at levels that we don’t allow outdoors

Cooking and Weight gain

Cooking is a universal human behaviour that has been proposed to function partly as a mechanism for increasing dietary net energy gain and Research shows that cooked foods are a major contributing factor to the epidemic weight gain and obesity crisis we see now. A long time ago farmers found out that animals eating raw food put on a lot of lean mass but not much fat or the weight needed to make good profits. So farmers started processing the food to get bigger weight gains. On experiments feeding mice processed grains put on significantly more weight and became obese compared to mice fed whole grains in their natural unprocessed form.

An explanation for this is that processing and cooking increases the energy gained from carbohydrate, protein and fat sources. In fats the cellular structure of many foods constrains their digestibility. For example, Oilseeds have cell walls composed mainly of indigestible non-starch polysaccharides and store their lipids in oil bodies, intracellular, spherical organelles coated by oleosin proteins. These features hinder digestive lipases from accessing the encapsulated lipids which may explain why unprocessed (raw/whole; RW) nuts and other oilseeds have high measured lipid and energy content, but display lower digestibility. Cooking and/or mechanical processing tears cell walls and disrupts oil bodies, promoting lipid release which shows that processing could increase lipid digestibility, because, unguarded by cell walls and oleosins, the freed lipids are likely more accessible to lipases.

Prebiotics through the metabolism of the gut microbiome have also been linked to satiety effects and foods that contain fiber, protein, and plant-based fat tend to be the most filling. These nutrients slow down digestion and the absorption of nutrients, a process that helps you feel physically full for longer, and also means lower blood sugar and insulin spikes. While all unprocessed plant sources are rich in prebiotics leeks are rich in fructan and cellulose fibers (types of prebiotics) are long enough to survive all the way down the GI tract. However, cooking shortens the fiber chain, so it should be eaten raw or lightly cooked.

 

 

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