Sarcopenia is an age-related loss of muscle mass and strength. Coffee has antioxidant and anti-inflammatory properties that have been shown to be inversely related to the mechanism of sarcopenia. In animal studies coffee attenuated the reduction of age-related muscle weight and muscle power, and stimulated regeneration of injured muscle compared to controls. Furthermore, pro-inflammatory mediators such as tumor necrosis factor-alpha and interleukin 6 decreased after coffee treatment
In this study with a sample consisted of 1,781 men who were at least 60 years of age, compared to the group of individuals who drank less than one cup of coffee a day, people who consumed at least 3 cups showed a 57% decreased sarcopenia. Good news for the coffee drinkers was that the decrease was not significant when the daily coffee consumption was 1 or 2 cups. The results of this study suggest that consuming at least 3 cups of coffee per day was associated with a lower prevalence of sarcopenia in elderly elderly men.
Coffee has phenolic compounds such as chlorogenic acid and caffeic acid that have strong antioxidant activity and anti-inflammatory effects. A number of studies have now shown habitual coffee consumption is associated with lower prevalence of diabetes or pre-diabetes, insulin resistance, stroke, Parkinson's disease, and cardiovascular disease. There is also evidence that coffee consumption is associated with decreased risks for some types of cancer. Not to mention the antiaging effect I recently reported on my posts.
Sarcopenia is the progressive loss of muscle mass and strength as we age. Several factors are related to the pathogenesis of sarcopenia. Age-related changes such as decreased levels and sensitivity of anabolic hormones, lack of physical activity, nutritional deficiencies, and comorbid diseases all contribute to the onset and progression of sarcopenia. These changes are hypothesized to lead inflammation with increased circulating levels of inflammatory cytokines, oxidative stress, suppressed muscle autophagy, and increased apoptosis by altering intra- and extracellular processes. In addition, oxidative metabolism generates reactive oxygen species, which alters skeletal muscle mitochondrial DNA and can lead to sarcopenia.