Since 2006 there has been a large body of scientific evidence showing the gut microbiota is interlinked with obesity and other metabolic conditions including type 2 diabetes. Probiotics are live micro-organisms that confer health benefits to the host and prebiotics are fibers that selectively improve the growth of beneficial gut microbes. Previous animal studies have shown probiotics prevented weight gain, improved insulin sensitivity, as well as reduced endotoxemia and tissue inflammation
In a study of 225 healthy volunteers randomized into four groups those taking the prebiotic with the probiotic or the probiotic alone improved weight. The prebiotic with probiotic group showed a − 4.5% or 1.4 kg difference to the Placebo group, and the probiotic group alone had a − 3.0 reduction in body fat. Changes in fat mass were most pronounced in the abdominal region, and were reflected by similar changes in waist circumference. Both groups also saw a reduction in inflammation.
This clinical trial demonstrates that a probiotic product with or without dietary fiber controls body fat mass and also reduced waist circumference and food intake.